At CBD Shipt we have made a point to try and bring you the most up to date facts and theories
regarding the use of CBD oils and the medicinal effects they contain – all backed by actual
scientific studies. We have explored CBD oils in treatments for issues ranging from glaucoma
and skincare, to even the possibility of it being used as a treatment for your pet's medical
issues. After these articles went up, we started getting a significant amount of questions and
opinions regarding a whole slew of different diseases. One of the most commonly discussed
issues regarding CBD is its effects regarding cancers. We have briefly touched on the topic, but
it seems about time we really dive into the possibilities.
For this article, we are going to explore some of the most promising studies so far regarding
cancer and what they mean for the future prospects of CBD use.
Reduction of Tumor Growth
● Study #1: Cannabidiol and Angiogenesis
“Cannabidiol Inhibits Angiogenesis by Multiple Mechanisms.”
British Journal of Pharmacology, vol. 167, no. 6, 2012, pp. 1218–1231.,
This study from the University of Insubria in Italy explored the “anti-proliferative and pro-
apoptotic actions of cannabinoids on various tumors” i.e., CBD’s ability to limit the growth of
tumors and cell death.
Their result: The study concluded that CBD does inhibit the proliferation of cancerous tumor
cells through multiple mechanisms. They punctuated the study by saying that this supports the
theory that: “CBD has potential as an effective agent in cancer therapy.”

● Study #2: Effects on Human Breast Carcinoma
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human
breast carcinoma.
J Pharmacol Exp Ther. 2006 Sep;318(3):1375-87. Epub 2006 May 25.
These researchers went into the study aware of the anti-tumor ability of Tetrahydrocannabinol (THC)
but lamented that the psychotropic effects of THC limited its use in treatments. The researchers then
took cannabidiol, cannabichromene, cannabidiol acid, cannabigerol, and THC acid to see of their
was a way to propagate those same positive effects with minimal psychotropic side effects.

Their result: The study found that “Results … Indicate that, of natural compounds tested, cannabidiol
is the most potent inhibitor of cancer cell growth” They also found that CBD was able to limit the
growth of both breast cancer and lung cancer cells in test animals. They also stated that “Our data
support the further testing of cannabidiol and cannabidiol-rich extracts for the potential treatment of
cancer.”

● Study #3: Effects on Brain cancer Growth
A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
British Journal of Cancer | Published online 27 June 2006
The primary goal of this study was to try and recreate the positive effects of CBD on Cancer cell growth
found in animal subjects, in human patients. They used nine patients with glioblastoma multiforme, a form
of brain cancer, who had not responded to surgery and radiotherapy and continued to have tumor
progression.
Their results: Of the nine, two of the patients experienced a reduction in tumor growth after the application
of a Tetrahydrocannabinol treatment. This was enough for the researchers to suggest further exploration
in future trials.

● Study #4: Cancer Pain Management
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy,
safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-
related pain.
This study matched CBD up against a placebo in order to measure the effective pain relief qualities. They
got 177 patients who were experiencing pain related to their cancer and gave them either a dose of THC:
CBD extract, THC extract, or a placebo over the course of two-weeks. They rated the effects via a
Numerical Rating Scale (NRS) score.
Their results: It was found that the CBD extract had a significant effect on pain relief when compared to
both the THC extract and the placebo. “THC: CBD showed a reduction of more than 30% from baseline
pain NRS score when compared with placebo…This study shows that THC: CBD extract is effective for
pain relief in patients with advanced cancer pain not fully relieved by strong opioids.”

● Study #5: Effects on CBD on Oral Cancer
Cannabinoids inhibit cellular respiration of human oral cancer cells.
Pharmacology. 2010;85(6):328-35. doi: 10.1159/000312686. Epub 2010 Jun 2.
This study involved testing the efficacy of primary cannabinoids on oral cancer cells (Tu183) which are
highly resistant to traditional anticancer drugs. This study is admittedly beyond my ability to accurately

summarize, luckily the researchers gave a clear statement in their conclusion: “These results show the
cannabinoids are potent inhibitors of Tu183 cellular respiration and are toxic to this highly malignant
tumor.”

These studies all show the wide-ranging possibilities of CBD to help limit tumor growth and to manage
pain in cancer patients. These five were only a small selection of the vast array of studies showing similar
results. The conclusion of nearly every study states that there is a significant amount of promise
regarding the effects of CBD and future methods of cancer treatment.